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For research published in 2022 study in the journal Food and Chemical Toxicology, scientists examined “the genotoxicity and the intracellular reactive oxygen species induction by physiologically relevant concentrations of three different TiO2 nanomaterials in Caco-2 and HT29-MTX-E12 intestinal cells, while considering the potential influence of the digestion process in the NMs’ physiochemical characteristics.” They found a “DNA-damaging effect dependent on the nanomaterial,” along with the micronucleus assay suggesting “effects on chromosomal integrity, an indicator of cancer risk, in the HT29-MTX-E12 cells, for all the tested TiO2 nanomaterials.” Researchers concluded that the results showcase “evidence of concern” regarding titanium dioxide used as a food additive.
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Overall, titanium dioxide manufacturers play a crucial role in supplying this essential compound to industries around the world. By focusing on quality, sustainability, and innovation, manufacturers can ensure a stable supply of titanium dioxide for years to come.
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- Furthermore, anatase titanium dioxide offers good adhesion and dispersion characteristics, which facilitate the manufacturing process of coatings. Its fine particle size and uniform distribution ensure a smooth and consistent finish, while its compatibility with various binding agents and additives makes it easy to incorporate into different types of coatings formulations.
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TiO2 comes in many different forms. However, only a few of these forms are considered food-grade (acceptable to be added to food). Many studies that raised concern about the safety of TiO2, including the concern for genotoxicity, used forms of TiO2 that are not considered acceptable for use in food and have different properties than food-grade TiO2. Other studies did use food-grade TiO2, but took steps to break the material down into smaller particles than what would normally be found in food.
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Pigmentary TiO2 particles are approximately 200-350nm in dimension and this form accounts for 98 percent of total production. It is used mainly for light scattering and surface opacity applications. It is used as a base for various colour paints or as a standalone ‘brilliant’ white.
- Regardless of the process used, the production of titanium dioxide is tightly controlled to ensure consistent quality and to meet stringent environmental regulations. Modern facilities are equipped with advanced pollution control technologies to minimize emissions and waste. Additionally, the industry has made strides in developing more sustainable practices, such as using solar energy to power some of the reactions or recovering and recycling byproducts.
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By reducing processed foods in your diet, you can reduce the likelihood of not only eating titanium dioxide but eating other chemicals of concern, Faber said, noting that consumers can also call their elected representatives urging them to support increased food safety legislation and take action with organization alliances like Toxic Free Food FDA. America, once again, is falling behind the rest of the world when it comes to chemical safety.
- The journey into this factory is like stepping into a futuristic world where technology and nature coexist harmoniously. The air is crisp and clean, devoid of the usual pollutants one might associate with heavy industry. This is no accident; the factory has invested heavily in state-of-the-art pollution control systems that ensure emissions are minimized, while also recovering and recycling materials wherever possible.
- The photocatalytic properties of titanium dioxide are particularly interesting. When exposed to ultraviolet radiation, TiO2 can catalyze reactions that decompose organic compounds, leading to its use in self-cleaning surfaces and air purification systems When exposed to ultraviolet radiation, TiO2 can catalyze reactions that decompose organic compounds, leading to its use in self-cleaning surfaces and air purification systems
When exposed to ultraviolet radiation, TiO2 can catalyze reactions that decompose organic compounds, leading to its use in self-cleaning surfaces and air purification systems When exposed to ultraviolet radiation, TiO2 can catalyze reactions that decompose organic compounds, leading to its use in self-cleaning surfaces and air purification systems
chemical titanium dioxide. This property is utilized in construction materials like concrete and glass, where the titanium dioxide helps to break down pollutants and reduce maintenance requirements.
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- Moreover, the development of new technologies has expanded the applications of titanium dioxide beyond its traditional uses. For example, nanotechnology has enabled the creation of titanium dioxide nanoparticles with enhanced properties, such as improved UV protection and antibacterial activity. These nanoparticles are being used in a variety of products, including textiles, electronics, and healthcare products.
What Is Titanium Dioxide?
Analyst Insight
Titanium dioxide (E171) is an additive that is used in food as a colour. The function of food colours is to make food more visually appealing, to give colour to food that would otherwise be colourless, or to restore the original appearance of food. Titanium dioxide is used to provide whiteness and opacity to foods.

Some websites maintain titanium dioxide is inferior to zinc oxide, another mineral sunscreen ingredient whose core characteristics are similar to those of titanium dioxide. The reality is that titanium dioxide is a great broad-spectrum SPF ingredient and is widely used in all manner of sun-protection products. What gets confusing for some consumers is trying to decipher research that ranks sunscreen ingredients by a UV spectrum graph. By most standards, broad-spectrum coverage for sunscreen ingredients is defined as one that surpasses 360 nanometers (abbreviated as “nm” - how the sun’s rays are measured). Titanium dioxide exceeds this range of protection, but depending on whose research you read, it either performs as well as or slightly below zinc oxide.


In beauty and personal care products, the ingredient is listed with its colour index (CI) number ‘CI 77891’. When nano grade titanium dioxide is used in our sunscreens, this is referenced as ‘titanium dioxide’ [nano] in the ingredients list.
In a 2020 study published in the Journal of Trace Elements in Medicine and Biology, researchers conducted an in vitro experiment to analyze the effects of TiO2 nanoparticles on a human neuroblastoma (SH-SY5Y) cell line. The scientists evaluated “reactive oxygen species (ROS) generation, apoptosis, cellular antioxidant response, endoplasmic reticulum stress and autophagy.” The results showed that exposure to the nanoparticles “induced ROS generation in a dose dependent manner, with values reaching up to 10 fold those of controls. Nrf2 nuclear localization and autophagy also increased in a dose dependent manner. Apoptosis increased by 4- to 10-fold compared to the control group, depending on the dose employed.”
Before engaging with a cheap titanium dioxide manufacturer, businesses should conduct thorough research. It is essential to assess the manufacturer’s reputation, quality control measures, and certifications. Making informed decisions can prevent potential issues related to subpar products, which can lead to problems in manufacturing processes and final product quality.
Used for coloring paint, ink, rubber, etc. Inorganic white pigments are widely used as white pigments in plastics such as polyolefin, vinyl resin, ABS resin, polystyrene, polycarbonate, nylon and polyformaldehyde, as well as paints and inks. It is less effective in polyurethane and amino resins, and less suitable in fluoroplastics. It is also used for coloring rubber products, papermaking, varnished cloth, oilcloth, leather, watercolor paints, paper, enamel, etc. Used as an adhesive in the production of electric beads.