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Even though it is one of the most-produced chemicals, the real and potential benefits of titanium dioxide are not without controversies. Dust inhalation may cause breathing problems. Titanium dioxide has been classified by the International Agency for Research on Cancer as an Group 2B carcinogen, a “possible carcinogen to humans,” based on studies of rats that inhaled the substance.
New Safety Rulings & Regulations
Lithopone is the ideal combination of the white pigment zinc sulfide and the white spacer Blanc fixe. Due to the particle distribution of the ZnS (0.35 µm) and BaSO4 (0.8 -1.0 µm), which is the result of a co-precipitation (not mixing) and co-calcination, a high packing density is achieved, which in turn gives Lithopone its low resin demand and excellent rheological properties.
Research has shown that, when ingested as a food additive, titanium dioxide and its nanoparticles can impact, alter, and/or damage important protective bacteria in the gut, along with the metabolic pathways of gut bacteria.
In 2021, the European Food Safety Authority concluded that titanium dioxide is no longer safe in foods due to the same concerns over nanoparticles. As a result, titanium dioxide is now banned as a food additive in the EU. Although studies have shown that the absorption of ingested titanium dioxide is low, evidence suggests that titanium dioxide nanoparticles can accumulate in the body over time. Health Canada deemed it safe in 2022 but noted concerns. Unlike their European counterparts, Canadian officials did not consider studies performed with titanium dioxide nanoparticles alone.
Titanium dioxide (TiO2) is a naturally occurring mineral that is mined from the earth, processed and refined, and added to a variety of foods, as well as other consumer products. White in color, it is used to enhance the color and sheen of certain foods and is also key for food safety applications. In its natural state it exists in different bulk crystalline forms, such as anatase and rutile, but during processing it is ground into a very fine powder.
In 2019, EFSA published a statement on the review of the risk related to the exposure to food additive titanium dioxide (E171) performed by the French Agency for Food, Environment and Occupational Health Safety (ANSES). In its statement, EFSA highlighted that the ANSES opinion reiterated the uncertainties and data gaps previously identified by EFSA and did not present findings that invalidated the Authority’s previous conclusions on the safety of titanium dioxide.


Following the EU’s ban on E171, the FDA told the Guardian that, based on current evidence, titanium dioxide as a food additive is safe. “The available safety studies do not demonstrate safety concerns connected to the use of titanium dioxide as a color additive.”
Why Did Europe Ban Titanium Dioxide?
If you want to avoid titanium dioxide, Stoiber and Faber urge consumers to try and avoid processed foods as best as you can.
Applications:
1. Paints and Coatings Due to its excellent opacity and brightness, anatase TiO2 is extensively used as a pigment in paints. The high refractive index of this compound allows for better coverage and durability, making it an essential component in decorative and protective coatings.

It's all over the place in our environment, said Dr. Johnson-Arbor.
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